Exploring Potential: Emerging Thresholds and Catalysts for the Future (HCWB, XRTX, VYNE, NRSN, CNTX)

In this week's list of five penny stocks, we aim to identify resistance breakthroughs and anticipate catalysts. Stay proactive in spotting potential upward shifts and precise entry points. Avoid chasing bottoms; exercise patience and await confirmation through a breakout.

HCW Biologics Inc. (NASDAQ: HCWB) - Last week, the company closed up 2% at 1.23. In November, they released positive business highlights, confirming consistent results in humans matching preclinical animal studies for HCW9218. The company aims to finish the initial phase of ongoing cancer studies in late 2023 or early 2024 and plans to submit an IND application for an autoimmune disorder trial by the end of 2023. We'll be closely monitoring both company updates and the potential breakout above the $1.33 resistance level.

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XORTX Therapeutics Inc. (NASDAQ: XRTX) - Last week, the company closed up 14% at $2.31. In August, they submitted an Orphan Drug Designation application for XORLO™ to the EMA, specifically for treating autosomal dominant polycystic kidney disease (ADPKD). The EMA's COMP office is set to review the application with a decision expected in December of 2023. We'll be monitoring company updates and watching for a potential resistance break at $2.49 for further upward momentum.

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VYNE Therapeutics Inc. (NASDAQ: VYNE) - Last week, the company closed down 6% at $2.33. In November of 2023, the CEO highlighted substantial progress, especially with positive Phase 1b trial results for VYN201 in vitiligo treatment. They're on schedule to submit the VYN202 IND by year-end 2023, initiating a Phase 1a trial in Q1 2024. If successful, Phase 1b trials for plaque psoriasis and adult-onset rheumatoid arthritis are planned for H2 2024. We'll be monitoring for a potential breakout above the $2.48 resistance level and anticipating future updates.

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NeuroSense Therapeutics Ltd. (NASDAQ: NRSN) - Last week, the company closed slightly under 1% higher at $0.78. In December of 2023, the company shared additional positive efficacy data from its Phase 2b trial (PARADIGM) of PrimeC for ALS. Primary biomarker results are anticipated in H1 2024. Discussions with regulatory agencies regarding PrimeC's effects and safety are planned for the End of Phase 2 meeting in H1 2024. Additionally, Neurofilament biomarker results from a collaboration with Biogen are expected in January 2024. We'll be watching for future updates and a potential resistance breakout in the $0.86-$0.87 range.

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Context Therapeutics Inc. (NASDAQ: CNTX) - Closing last week's trading session down approximately 1% at $1.13. In November, the company highlighted progress on CTIM-76, a Claudin 6 x CD3 bispecific antibody, moving towards its first-in-human clinical study. Preclinical data showcased CTIM-76's broad therapeutic potential against CLDN6-positive tumors, addressing limitations of current therapies. CEO Martin Lehr anticipates filing an IND with the FDA in late Q1 2024 for CTIM-76. We'll be monitoring for future updates and a potential resistance breakout around $1.24.

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